ea0029p803 | Endocrine tumours and neoplasia | ICEECE2012
Rossi V.
, Visconti D.
, Bellastella G.
, Palumbo V.
, Abbondanza C.
, De Rosa C.
, Bellastella A.
, Sinisi A.
The effects in vitro and in vivo of somatostatin (SS) analogues are linked to the presence of specific binding sites on target cells. Estradiol (E2) may modulate the expression of SS receptors (SSTR) in some cell models, including breast cancer and pituitary cells. Aim of this study was to evaluate the effects of E2 on SSTR1-5 ligand binding domains (LBD) expression levels in prostate epithelial cells (PEC).Methods: We investigated the effe...